Alternatively there are yellow buses running from "Nuremberg to Prague ":http://czech-transport.com/index.php?…. These buses are departing from the central train station in Nuremberg or from the Nuremberg airport. The journey takes 3h45min.
There are also buses runned by Deutsche Bahn. These buses (called DB Expressbus) run every two hours starting from 07:30 and last bus leaving 17:30. The buses require seat reservation. The journey takes 3h45min.
Hotels in Prague (Booking.com)
Hostels in Prague (HostelBookers.com)
Hotels in Nuremberg (Booking.com)
Hostels in Nuremberg (HostelBookers.com)
Last update: 2013-12-12